Xiamen Bioendo Technology, Co., Ltd. is a provider of in vitro diagnostic kits. We are the pioneer in the field of endotoxin detection by Tachypleus Amebocyte Lysate (TAL reagents).
Limulus Amebocyte Lysate (LAL) test was commercially introduced as a pyrogen detection reagent for injectable medication in the late 1970’s. Compare to Rabbit Pyrogen Test, LAL tests are less time consuming, easy to perform and more reliable. Today, LAL tests are widely used by the pharmaceutical and medical device industries around the world to ensure that their products, e.g., intravenous drugs, vaccines, and medical devices, are free of bacterial endotoxin contamination.
LAL reagents extracted from the blue blood of North American horseshoe crab, Limulus polyphemus were commonly known as LAL and the reagents extracted from Chinese horseshoe crab, Tachypleus tridentatus, were commonly known as TAL. Both LAL and TAL have the same function for endotoxin detection. In USP 28 chapter 85 Bacterial Endotoxins Test, “Limulus Amebocyte Lysate (LAL) obtained from the aqueous exacts of circulating amebocytes of horseshoe crab (Limulus Polyphemus or Tachypleus tridentatus) which has been prepared and characterized for use as an LAL Reagent”, so we usually call the TAL Reagent as LAL Reagent.